The 71-year-old leader of the Roman Catholic Church had the lower lobe of his right lung removed on October 13 and was diagnosed with lung adenocarcinoma, the most common form of lung cancer.
Final histological and molecular biology test results have confirmed that "the tumor was a pulmonary adenocarcinoma and that the disease was localised" and had not spread, the doctors said in a statement released by the Vatican.
A follow-up oncological evaluation also "confirmed that no further treatment is necessary," the pope’s lead surgeon, Stefano Margaritora, and his personal physician, Luigi Carbone, said.
However, it was still unclear whether the pope would proceed with a planned trip to Uruguay, Argentina and Peru, scheduled for November 6-17.
Leo was discharged from Rome's Gemelli hospital on Saturday, four days after his operation, and the Vatican said he would gradually resume his activities.
On Wednesday, he returned to St. Peter's Square for his weekly audience with pilgrims.
Margaritora said last week there were "no clinical reasons" preventing the pope from travelling to South America, but the Vatican’s secretary of state has indicated the pontiff may need to adjust the pace of his schedule to aid his recovery.
In May last year, Leo became the first US-born leader of the Roman Catholic Church.
(pg/gs)