The top-placed Polish cyclist, Rafał Majka, took fourth place, missing out on a podium spot by four seconds.
Danish rider Jakob Fuglsang finished second, ahead of Britain’s Simon Yates.
Evenepoel’s win in the Tour de Pologne was all but sealed after a bold performance on Saturday around the southern town of Bukowina Tatrzańska, when he broke away from the rest of the pack and finished almost two minutes ahead of Fuglsang.
The 2020 Tour de Pologne started on Wednesday with sanitary precautions in place amid the coronavirus pandemic.
Meanwhile, Dutch cyclist Fabio Jakobsen, badly injured in a horrific finish-line crash during the first stage of this year’s Tour de Pologne, has been brought out of an induced coma by doctors at a hospital in the southern Polish city of Sosnowiec.
Doctors said on Friday Jakobsen was in “good” condition after undergoing a complicated five-hour operation involving oral surgeons and ear, nose and throat specialists.
The rider had suffered extensive craniofacial injuries and was resuscitated at the scene of the crash in Katowice, southern Poland, earlier this week.