Ukraine's air force said it shot down two ballistic missiles fired from the Russian-occupied Crimea peninsula.
Falling debris damaged a three-story building in central Kyiv and a string of explosions rang out across the city, the Reuters news agency reported.
At least five people were injured as a result of the attack, according to a report by Ukrainian state news agency Ukrinform.
Debris also fell in Kyiv's Solomyansky, Holosiyvsky and Dnipro districts, officials said, as cited by Reuters.
'Ukraine needs our assistance now': US ambassador
The US ambassador to Kyiv, Bridget Brink, said in an X post that Russia had used hypersonic missiles to attack the Ukrainian capital.
"Over the last five days, Russia has launched hundreds of missiles and drones against a sovereign country," she said.
"Ukraine needs our assistance now," Brink added. "There is not a moment to lose."
Russia invaded Ukraine on February 24, 2022, starting the largest armed conflict in Europe since World War II.
Monday is day 761 of Russia’s war on Ukraine.
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Source: ukrinform.net, Reuters, IAR, PAP